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Intravenous Delivery of Targeted Liposomes to Amyloid-β Pathology in APP/PSEN1 Transgenic Mice
Extracellular amyloid-β (Aβ) plaques and intracellular neurofibrillary tangles constitute the major neuropathological hallmarks of Alzheimer’s disease (AD). It is now apparent that parenchymal Aβ plaque deposition precedes behavioral signs of disease by several years. The development of agents that...
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Auteurs principaux: | , , , , , , , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
Public Library of Science
2012
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3485335/ https://ncbi.nlm.nih.gov/pubmed/23119043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048515 |
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