High Resolution Size Analysis of Fetal DNA in the Urine of Pregnant Women by Paired-End Massively Parallel Sequencing

BACKGROUND: Fetal DNA in maternal urine, if present, would be a valuable source of fetal genetic material for noninvasive prenatal diagnosis. However, the existence of fetal DNA in maternal urine has remained controversial. The issue is due to the lack of appropriate technology to robustly detect th...

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Главные авторы: Tsui, Nancy B. Y., Jiang, Peiyong, Chow, Katherine C. K., Su, Xiaoxi, Leung, Tak Y., Sun, Hao, Chan, K. C. Allen, Chiu, Rossa W. K., Lo, Y. M. Dennis
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485143/
https://ncbi.nlm.nih.gov/pubmed/23118982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048319
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