Specification, annotation, visualization and simulation of a large rule-based model for ERBB receptor signaling

BACKGROUND: Mathematical/computational models are needed to understand cell signaling networks, which are complex. Signaling proteins contain multiple functional components and multiple sites of post-translational modification. The multiplicity of components and sites of modification ensures that in...

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Detalhes bibliográficos
Main Authors: Creamer, Matthew S, Stites, Edward C, Aziz, Meraj, Cahill, James A, Tan, Chin Wee, Berens, Michael E, Han, Haiyong, Bussey, Kimberley J, Von Hoff, Daniel D, Hlavacek, William S, Posner, Richard G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485121/
https://ncbi.nlm.nih.gov/pubmed/22913808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-107
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