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Simulation of large-scale rule-based models

Motivation: Interactions of molecules, such as signaling proteins, with multiple binding sites and/or multiple sites of post-translational covalent modification can be modeled using reaction rules. Rules comprehensively, but implicitly, define the individual chemical species and reactions that molec...

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Detalhes bibliográficos
Main Authors: Colvin, Joshua, Monine, Michael I., Faeder, James R., Hlavacek, William S., Von Hoff, Daniel D., Posner, Richard G.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660871/
https://ncbi.nlm.nih.gov/pubmed/19213740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp066
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