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Purification from rat sarcolemma of the saxitoxin-binding component of the excitable membrane sodium channel.

The saxitoxin-binding component (SBC) of the excitable membrane sodium channel has been solubilized and purified from rat skeletal muscle sarcolemma. Phospholipid was required in mixed micelles with detergent for stability of the mammalian SBC. Even at optimal detergent-to-phospholipid ratio, the so...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Barchi, R L, Cohen, S A, Murphy, L E
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1980
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348483/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6246486/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.3.1306
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