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Characteristics of saxitoxin binding to the sodium channel of sarcolemma isolated from rat skeletal muscle.

1. The characteristics of saxitoxin (STX) binding to the mammalian Na channel have been studied in purified sarcolemma isolated from rat skeletal muscle. 2. STX binds specifically to isolated sarcolemma with a Kd of 1.43 x 10(-9) M and Bmax of 7-8 p-mole STX bound/mg membrane protein at 0 degrees C...

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Bibliographic Details
Main Authors: Barchi, R L, Weigele, J B
Format: Artigo
Language:Inglês
Published: 1979
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1279052/
https://ncbi.nlm.nih.gov/pubmed/42783
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