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Purification from rat sarcolemma of the saxitoxin-binding component of the excitable membrane sodium channel.

The saxitoxin-binding component (SBC) of the excitable membrane sodium channel has been solubilized and purified from rat skeletal muscle sarcolemma. Phospholipid was required in mixed micelles with detergent for stability of the mammalian SBC. Even at optimal detergent-to-phospholipid ratio, the so...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Barchi, R L, Cohen, S A, Murphy, L E
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1980
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348483/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6246486/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.3.1306
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