Adenoviral 15-lipoxygenase-1 gene transfer inhibits hypoxia-induced proliferation of retinal microvascular endothelial cells in vitro

AIM: To investigate whether 15-Lipoxygenase-1 (15-LOX-1) plays an important role in the regulation of angiogenesis, inhibiting hypoxia-induced proliferation of retinal microvascular endothelial cells (RMVECs) and the underlying mechanism. METHODS: Primary RMVECs were isolated from the retinas of C57...

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Bibliographische Detailangaben
Hauptverfasser: Yan, Ying, He, Tao, Shen, Ying, Chen, Xiao, Diao, Bo, Li, Zhi, Liu, Qing, Xing, Yi-Qiao
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Journal of Ophthalmology Press 2012
Schlagworte:
Basic Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484709/
https://ncbi.nlm.nih.gov/pubmed/23166865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3980/j.issn.2222-3959.2012.05.04
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