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Tpl2 regulates intestinal myofibroblast HGF release to suppress colitis-associated tumorigenesis
The tumor microenvironment plays a significant role in colitis-associated cancer (CAC). Intestinal myofibroblasts (IMFs) are cells in the intestinal lamina propria secreting factors that are known to modulate carcinogenesis; however, the physiological role of IMFs and signaling pathways influencing...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Clinical Investigation
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3484449/ https://ncbi.nlm.nih.gov/pubmed/23064365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63917 |
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