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IKKβ in intestinal mesenchymal cells promotes initiation of colitis-associated cancer

The importance of mesenchymal cells in inflammation and/or neoplastic transformation is well recognized, but their role in the initiation of these processes, particularly in the intestine, remains elusive. Using mouse models of colorectal cancer, we show that IKKβ in intestinal mesenchymal cells (IM...

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Bibliografske podrobnosti
izdano v:J Exp Med
Main Authors: Koliaraki, Vasiliki, Pasparakis, Manolis, Kollias, George
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683996/
https://ncbi.nlm.nih.gov/pubmed/26621453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150542
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