Dendritic cells tolerized with adenosine A(2A)R agonist attenuate acute kidney injury

DC-mediated NKT cell activation is critical in initiating the immune response following kidney ischemia/reperfusion injury (IRI), which mimics human acute kidney injury (AKI). Adenosine is an important antiinflammatory molecule in tissue inflammation, and adenosine 2A receptor (A(2A)R) agonists prot...

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Detalhes bibliográficos
Main Authors: Li, Li, Huang, Liping, Ye, Hong, Song, Steven P., Bajwa, Amandeep, Lee, Sang Ju, Moser, Emily K., Jaworska, Katarzyna, Kinsey, Gilbert R., Day, Yuan J., Linden, Joel, Lobo, Peter I., Rosin, Diane L., Okusa, Mark D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484444/
https://ncbi.nlm.nih.gov/pubmed/23093781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63170
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