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Glycine receptor mutants of the mouse: what are possible routes of inhibitory compensation?

Defects in glycinergic inhibition result in a complex neuromotor disorder in humans known as hyperekplexia (OMIM 149400) with similar phenotypes in rodents characterized by an exaggerated startle reflex and hypertonia. Analogous to genetic defects in humans single point mutations, microdeletions, or...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schaefer, Natascha, Vogel, Nicolas, Villmann, Carmen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484359/
https://ncbi.nlm.nih.gov/pubmed/23118727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2012.00098
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