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A Divalent Ion Is Crucial in the Structure and Dominant-Negative Function of ID Proteins, a Class of Helix-Loop-Helix Transcription Regulators

Inhibitors of DNA binding and differentiation (ID) proteins, a dominant-negative group of helix-loop-helix (HLH) transcription regulators, are well-characterized key players in cellular fate determination during development in mammals as well as Drosophila. Although not oncogenes themselves, their u...

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Detalhes bibliográficos
Main Authors: Wong, Marie Vivian, Jiang, Sizun, Palasingam, Paaventhan, Kolatkar, Prasanna R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484135/
https://ncbi.nlm.nih.gov/pubmed/23119064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048591
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