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Rearrangement of immunoglobulin gamma 1-chain gene and mechanism for heavy-chain class switch.

Cloning and nucleotide sequence determination suggest that the rearranged gamma 1-chain gene in a gamma 1-chain-producing myeloma a-pears to be formed by the recombination between the 5' flanking regions of the gamma 1- and mu-chain genes of undifferentiated cells. The recombination site is dis...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Kataoka, T, Kawakami, T, Takahashi, N, Honjo, T
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1980
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348393/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6767246/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.2.919
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