Rearrangement of immunoglobulin gamma 1-chain gene and mechanism for heavy-chain class switch.
Cloning and nucleotide sequence determination suggest that the rearranged gamma 1-chain gene in a gamma 1-chain-producing myeloma a-pears to be formed by the recombination between the 5' flanking regions of the gamma 1- and mu-chain genes of undifferentiated cells. The recombination site is distinct...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1980
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348393/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6767246/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.2.919 |
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