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Rearrangement of immunoglobulin gamma 1-chain gene and mechanism for heavy-chain class switch.

Cloning and nucleotide sequence determination suggest that the rearranged gamma 1-chain gene in a gamma 1-chain-producing myeloma a-pears to be formed by the recombination between the 5' flanking regions of the gamma 1- and mu-chain genes of undifferentiated cells. The recombination site is dis...

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Detalhes bibliográficos
Main Authors: Kataoka, T, Kawakami, T, Takahashi, N, Honjo, T
Formato: Artigo
Idioma:Inglês
Publicado em: 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC348393/
https://ncbi.nlm.nih.gov/pubmed/6767246
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