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Characterization of double-stranded-RNA-activated kinase that phosphorylates α subunit of eukaryotic initiation factor 2 (eIF-2α) in reticulocyte lysates

Incubation of reticulocyte lysates with low levels of double-stranded (ds) RNA (1-20 ng/ml) activates a cAMP-independent protein kinase (dsI) that phosphorylates the α-subunit (M(r) 38,000) of initiation factor 2 (eIF-2) and produces an inhibition of protein chain initiation similar to that caused b...

詳細記述

保存先:
書誌詳細
主要な著者: Levin, Daniel H., Petryshyn, Ray, London, Irving M.
フォーマット: Artigo
言語:Inglês
出版事項: 1980
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC348375/
https://ncbi.nlm.nih.gov/pubmed/6928683
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