Characterization of double-stranded-RNA-activated kinase that phosphorylates α subunit of eukaryotic initiation factor 2 (eIF-2α) in reticulocyte lysates
Incubation of reticulocyte lysates with low levels of double-stranded (ds) RNA (1-20 ng/ml) activates a cAMP-independent protein kinase (dsI) that phosphorylates the α-subunit (M(r) 38,000) of initiation factor 2 (eIF-2) and produces an inhibition of protein chain initiation similar to that caused b...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1980
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348375/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6928683/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.2.832 |
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