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Electroporation- and Mechanical Ventilation-Mediated Gene Transfer to the Lung

Our lab has previously demonstrated that cytoplasmic trafficking and subsequent nuclear entry of non-viral plasmid DNA can be significantly enhanced through the application of cyclic stretch following transfection in vitro (1,2). Here, we demonstrate that cyclic stretching of the murine lung using v...

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Autors principals: Kaufman, Christopher D., Geiger, R. Christopher, Dean, David A.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483646/
https://ncbi.nlm.nih.gov/pubmed/20428212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2010.57
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