Signal-induced disassembly of the SCF ubiquitin ligase complex by Cdc48/p97

A large group of E3 ubiquitin ligases is formed by the multisubunit SCF complex, whose core complex (Rbx1/Cul1-Cdc53/Skp1) binds one of many substrate recruiting F-box proteins to form an array of SCF ligases with diverse substrate specificities. It has long been thought that ubiquitylation by SCF l...

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Bibliografiska uppgifter
Huvudupphovsmän: Yen, James L., Flick, Karin, Papagiannis, Christie V., Mathur, Radhika, Tyrrell, An, Ouni, Ikram, Kaake, Robyn M., Huang, Lan, Kaiser, Peter
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483439/
https://ncbi.nlm.nih.gov/pubmed/23000173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.08.015
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