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Signal-induced disassembly of the SCF ubiquitin ligase complex by Cdc48/p97
A large group of E3 ubiquitin ligases is formed by the multisubunit SCF complex, whose core complex (Rbx1/Cul1-Cdc53/Skp1) binds one of many substrate recruiting F-box proteins to form an array of SCF ligases with diverse substrate specificities. It has long been thought that ubiquitylation by SCF l...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3483439/ https://ncbi.nlm.nih.gov/pubmed/23000173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.08.015 |
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