Macrophage Paraoxonase 2 regulates calcium homeostasis and cell survival under Endoplasmic Reticulum stress conditions and is sufficient to prevent the development of aggravated atherosclerosis in Paraoxonase 2 deficiency/apoE(−/−) mice on a Western diet

Paraoxonase 2 deficiency (PON2-def) alters mitochondrial function and exacerbates the development of atherosclerosis in mice. PON2 overexpression protects against ER stress in cell culture. In this paper, we examined the role of PON2 in the unexplored link between ER stress and mitochondrial dysfunc...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Devarajan, Asokan, Grijalva, Victor R, Bourquard, Noam, Meriwether, David, Imaizumi, Satoshi, Shin, Bo-Chul, Devaskar, Sherin U., Reddy, Srinivasa T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483415/
https://ncbi.nlm.nih.gov/pubmed/22864055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2012.06.020
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items