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Inhibition of the TWEAK/Fn14 pathway attenuates renal disease in nephrotoxic serum nephritis

Previously it was shown that the TNF superfamily member TWEAK (TNFSF12) acts through its receptor, Fn14, to promote proinflammatory responses in kidney cells, including the production of MCP-1, RANTES, IP-10 and KC. In addition, the TWEAK/Fn14 pathway promotes mesangial cell proliferation, vascular...

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Autors principals: Xia, Yumin, Campbell, Sean R., Broder, Anna, Herlitz, Leal, Abadi, Maria, Wu, Ping, Michaelson, Jennifer S., Burkly, Linda C., Putterman, Chaim
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483377/
https://ncbi.nlm.nih.gov/pubmed/22982296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2012.08.008
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