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Inhibition of the TWEAK/Fn14 pathway attenuates renal disease in nephrotoxic serum nephritis
Previously it was shown that the TNF superfamily member TWEAK (TNFSF12) acts through its receptor, Fn14, to promote proinflammatory responses in kidney cells, including the production of MCP-1, RANTES, IP-10 and KC. In addition, the TWEAK/Fn14 pathway promotes mesangial cell proliferation, vascular...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3483377/ https://ncbi.nlm.nih.gov/pubmed/22982296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2012.08.008 |
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