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Inhibition of the TWEAK/Fn14 pathway attenuates renal disease in nephrotoxic serum nephritis

Previously it was shown that the TNF superfamily member TWEAK (TNFSF12) acts through its receptor, Fn14, to promote proinflammatory responses in kidney cells, including the production of MCP-1, RANTES, IP-10 and KC. In addition, the TWEAK/Fn14 pathway promotes mesangial cell proliferation, vascular...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Xia, Yumin, Campbell, Sean R., Broder, Anna, Herlitz, Leal, Abadi, Maria, Wu, Ping, Michaelson, Jennifer S., Burkly, Linda C., Putterman, Chaim
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2012
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483377/
https://ncbi.nlm.nih.gov/pubmed/22982296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2012.08.008
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