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CpG Island Structure and Trithorax/Polycomb Chromatin Domains in Human Cells
TrxG and PcG complexes play key roles in the epigenetic regulation of development through H3K4me3 and H3K27me3 modification at specific sites throughout the human genome, but how these sites are selected is poorly understood. We find that in pluripotent cells, clustered CpG-islands at genes predict...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3483364/ https://ncbi.nlm.nih.gov/pubmed/22819920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygeno.2012.07.006 |
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