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Cytotoxic Hydrophilic Iminophosphorane Coordination Compounds of d(8) Metals. Studies of their Interactions with DNA and HSA

The synthesis and characterization of a new water-soluble N,N-chelating iminophosphorane ligand TPA=N-C(O)-2-NC(5)H(4) (N,N-IM) (1) and its d(8) (Au(III), Pd(II) and Pt(II)) coordination complexes are reported. The structures of cationic [AuCl(2)(N,N-IM)] ClO(4) (2) and neutral [MCl(2)(N,N-IM)] M =...

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Detalhes bibliográficos
Main Authors: Carreira, Monica, Calvo-Sanjuán, Rubén, Sanaú, Mercedes, Zhao, Xiangbo, Magliozzo, Richard S., Marzo, Isabel, Contel, María
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483362/
https://ncbi.nlm.nih.gov/pubmed/23063789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2012.06.017
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