Usp14 Deficiency Increases Tau Phosphorylation without Altering Tau Degradation or Causing Tau-Dependent Deficits

Regulated protein degradation by the proteasome plays an essential role in the enhancement and suppression of signaling pathways in the nervous system. Proteasome-associated factors are pivotal in ensuring appropriate protein degradation, and we have previously demonstrated that alterations in one o...

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Detalhes bibliográficos
Main Authors: Jin, Youngnam N., Chen, Ping-Chung, Watson, Jennifer A., Walters, Brandon J., Phillips, Scott E., Green, Karen, Schmidt, Robert, Wilson, Julie A., Johnson, Gail V., Roberson, Erik D., Dobrunz, Lynn E., Wilson, Scott M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483306/
https://ncbi.nlm.nih.gov/pubmed/23144711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047884
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