Protective Antibody and CD8(+) T-Cell Responses to the Plasmodium falciparum Circumsporozoite Protein Induced by a Nanoparticle Vaccine

BACKGROUND: The worldwide burden of malaria remains a major public health problem due, in part, to the lack of an effective vaccine against the Plasmodium falciparum parasite. An effective vaccine will most likely require the induction of antigen specific CD8(+) and CD4(+) T-cells as well as long-la...

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Bibliographic Details
Main Authors: Kaba, Stephen A., McCoy, Margaret E., Doll, Tais A. P. F., Brando, Clara, Guo, Qin, Dasgupta, Debleena, Yang, Yongkun, Mittelholzer, Christian, Spaccapelo, Roberta, Crisanti, Andrea, Burkhard, Peter, Lanar, David E.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483151/
https://ncbi.nlm.nih.gov/pubmed/23144750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048304
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