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Linkage analyses of murine immunoglobulin heavy chain and serum prealbumin genes establish their location on chromosome 12 proximal to the T (5;12) 31H breakpoint in band 12F1.

Analysis of backcross mice carrying the Harwell translocation T(5;12)31H has led to the definitive localization of the immunoglobulin heavy chain gene cluster. Both Igh-1 and Pre-1 loci were found to segregate in tight linkage with the chromosomal markers 5(12) and 12(5), which define the balanced t...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Meo, T, Johnson, J, Beechey, C V, Andrews, S J, Peters, J, Searle, A G
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1980
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348310/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6767238/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.1.550
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