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Homologous recombination between transferred and chromosomal immunoglobulin kappa genes.

Homologous recombination between transferred and chromosomal DNAs provides a means of introducing well-defined, predetermined changes in the chromosomal genes. Here we report that this approach can be used to specifically modify the immunoglobulin genes in mouse hybridoma cells. The test system is b...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Baker, M D, Shulman, M J
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 1988
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365472/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3141782/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.10.4041
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