Homologous recombination between transferred and chromosomal immunoglobulin kappa genes.

Homologous recombination between transferred and chromosomal DNAs provides a means of introducing well-defined, predetermined changes in the chromosomal genes. Here we report that this approach can be used to specifically modify the immunoglobulin genes in mouse hybridoma cells. The test system is b...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Baker, M D, Shulman, M J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1988
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365472/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3141782/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.10.4041-4047.1988
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