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TAp63 is a master transcriptional regulator of lipid and glucose metabolism
TAp63 prevents premature aging suggesting a link to genes that regulate longevity. Further characterization of TAp63−/− mice revealed that these mice develop obesity, insulin resistance, and glucose intolerance, similar to those seen in mice lacking two key metabolic regulators, Silent information r...
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| मुख्य लेखकों: | , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2012
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3483083/ https://ncbi.nlm.nih.gov/pubmed/23040072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2012.09.006 |
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