TAp63 prevents premature aging by promoting adult stem cell maintenance

The cellular mechanisms that regulate the maintenance of adult tissue stem cells are still largely unknown. We show here that the p53 family member, TAp63, is essential for maintenance of epidermal and dermal precursors and that, in its absence, these precursors senesce and skin ages prematurely. Sp...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Su, Xiaohua, Paris, Maryline, Gi, Young Jin, Tsai, Kenneth Y., Cho, Min Soon, Lin, Yu-Li, Biernaskie, Jeffrey A., Sinha, Satrajit, Prives, Carol, Pevny, Larysa H., Miller, Freda D., Flores, Elsa R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418222/
https://ncbi.nlm.nih.gov/pubmed/19570515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2009.04.003
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items