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A Critical and Cell-Autonomous Role for MeCP2 in Synaptic Scaling Up

Rett syndrome (Rett) is the leading genetic cause of mental retardation in females. Most cases of Rett are caused by loss-of-function mutations in the gene coding for the transcriptional regulator methyl-CpG binding protein 2 (MeCP2), but despite much effort, it remains unclear how a loss of MeCP2 f...

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Detalhes bibliográficos
Main Authors: Blackman, Melissa P., Djukic, Biljana, Nelson, Sacha B., Turrigiano, Gina G.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483036/
https://ncbi.nlm.nih.gov/pubmed/23015442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3077-12.2012
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