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Triplicated alpha-globin loci in humans.

We have identified 12 individuals who are heterozygous for a chromosome with three alpha-globin genes. We determined the presence of the third alpha-globin locus by restriction endonuclease digestion and hybridization with alpha-globin cDNA probes. The three alpha-globin loci resided in an elongated...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Goossens, M, Dozy, A M, Embury, S H, Zachariades, Z, Hadjiminas, M G, Stamatoyannopoulos, G, Kan, Y W
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1980
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348303/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6928643/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.1.518
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