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Triplicated alpha-globin loci in humans.

We have identified 12 individuals who are heterozygous for a chromosome with three alpha-globin genes. We determined the presence of the third alpha-globin locus by restriction endonuclease digestion and hybridization with alpha-globin cDNA probes. The three alpha-globin loci resided in an elongated...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Goossens, M, Dozy, A M, Embury, S H, Zachariades, Z, Hadjiminas, M G, Stamatoyannopoulos, G, Kan, Y W
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1980
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348303/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6928643/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.1.518
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