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Activated G(s) signaling in osteoblastic cells alters the hematopoietic stem cell niche in mice

Adult hematopoiesis occurs primarily in the BM space where hematopoietic cells interact with stromal niche cells. Despite this close association, little is known about the specific roles of osteoblastic lineage cells (OBCs) in maintaining hematopoietic stem cells (HSCs), and how conditions affecting...

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Hlavní autoři: Schepers, Koen, Hsiao, Edward C., Garg, Trit, Scott, Mark J., Passegué, Emmanuelle
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482855/
https://ncbi.nlm.nih.gov/pubmed/22859604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-11-395418
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