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Normal and Leukemic Stem Cell Niches: Insights and Therapeutic Opportunities

Hematopoietic stem cells (HSC) rely on instructive cues from the bone marrow (BM) niche to maintain their quiescence and adapt blood production to the organism’s needs. Alterations in the BM niche are commonly observed in blood malignancies and directly contribute to the aberrant function of disease...

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Publicado en:Cell Stem Cell
Autores principales: Schepers, Koen, Campbell, Timothy B., Passegué, Emmanuelle
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4391962/
https://ncbi.nlm.nih.gov/pubmed/25748932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2015.02.014
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