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Normal and Leukemic Stem Cell Niches: Insights and Therapeutic Opportunities

Hematopoietic stem cells (HSC) rely on instructive cues from the bone marrow (BM) niche to maintain their quiescence and adapt blood production to the organism’s needs. Alterations in the BM niche are commonly observed in blood malignancies and directly contribute to the aberrant function of disease...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Schepers, Koen, Campbell, Timothy B., Passegué, Emmanuelle
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4391962/
https://ncbi.nlm.nih.gov/pubmed/25748932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2015.02.014
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