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Normal and Leukemic Stem Cell Niches: Insights and Therapeutic Opportunities
Hematopoietic stem cells (HSC) rely on instructive cues from the bone marrow (BM) niche to maintain their quiescence and adapt blood production to the organism’s needs. Alterations in the BM niche are commonly observed in blood malignancies and directly contribute to the aberrant function of disease...
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| Udgivet i: | Cell Stem Cell |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4391962/ https://ncbi.nlm.nih.gov/pubmed/25748932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2015.02.014 |
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