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Activated G(s) signaling in osteoblastic cells alters the hematopoietic stem cell niche in mice

Adult hematopoiesis occurs primarily in the BM space where hematopoietic cells interact with stromal niche cells. Despite this close association, little is known about the specific roles of osteoblastic lineage cells (OBCs) in maintaining hematopoietic stem cells (HSCs), and how conditions affecting...

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Bibliografiska uppgifter
Huvudupphovsmän: Schepers, Koen, Hsiao, Edward C., Garg, Trit, Scott, Mark J., Passegué, Emmanuelle
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482855/
https://ncbi.nlm.nih.gov/pubmed/22859604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-11-395418
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