Deficiency of the Calcium-Sensing Receptor in the Kidney Causes Parathyroid Hormone–Independent Hypocalciuria

Rare loss-of-function mutations in the calcium-sensing receptor (Casr) gene lead to decreased urinary calcium excretion in the context of parathyroid hormone (PTH)–dependent hypercalcemia, but the role of Casr in the kidney is unknown. Using animals expressing Cre recombinase driven by the Six2 prom...

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Detaylı Bibliyografya
Asıl Yazarlar: Toka, Hakan R., Al-Romaih, Khaldoun, Koshy, Jacob M., DiBartolo, Salvatore, Kos, Claudine H., Quinn, Stephen J., Curhan, Gary C., Mount, David B., Brown, Edward M., Pollak, Martin R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Nephrology 2012
Konular:
Basic Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482734/
https://ncbi.nlm.nih.gov/pubmed/22997254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012030323
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