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Vitamin K1 enhances sorafenib-induced growth inhibition and apoptosis of human malignant glioma cells by blocking the Raf/MEK/ERK pathway

BACKGROUND: The combined effects of anticancer drugs with nutritional factors against tumor cells have been reported previously. This study characterized the efficacy and possible mechanisms of the combination of sorafenib and vitamin K1 (VK1) on glioma cell lines. METHODS: We examined the effects o...

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Bibliografske podrobnosti
Main Authors: Du, Wei, Zhou, Jing-ru, Wang, Dong-liang, Gong, Kai, Zhang, Qing-jun
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482596/
https://ncbi.nlm.nih.gov/pubmed/22520038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7819-10-60
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