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Sorafenib combined vitamin k induces apoptosis in human pancreatic cancer cell lines through RAF/MEK/ERK and c-Jun NH2-terminal kinase pathways

Apoptosis has been shown to be induced by many agents, including the clinically useful Sorafenib and K vitamins (VKs). Since few agents have activity against pancreas cancer cell growth, we evaluated the role of naturally-occurring K vitamins and Sorafenib both independently and together on the grow...

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Autors principals: Wei, Gang, Wang, Meifang, Carr, Brian I.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896250/
https://ncbi.nlm.nih.gov/pubmed/20301194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22099
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