Upregulated TCRζ Enhances Interleukin-2 Production in T-Cells from Patients with CML

T-cell immunodeficiency is a common feature in patients with chronic myeloid leukemia (CML), and deficiency in CD3 levels was detected in T cells from these patients, which may represent a characteristic that is related to a lower T cell activation. In this study, we explored the possibility that fo...

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Autors principals: Zha, Xianfeng, Chen, Shaohua, Yang, Lijian, Shi, Li, Li, Bo, Wu, Xiuli, Lu, Yuhong, Li, Yangqiu
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2012
Matèries:
Molecular Mechanisms of Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482374/
https://ncbi.nlm.nih.gov/pubmed/23057733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dna.2012.1798
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