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Scrib regulates HGF-mediated epithelial morphogenesis and is stabilized by Sgt1–HSP90

Scribble was originally identified as a Drosophila protein that regulates epithelial polarity and formation of the basolateral surface. The mammalian orthologue, Scrib, is evolutionarily conserved, but does not appear to be necessary for apical-basolateral epithelial polarity. Instead, it is implica...

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Detalles Bibliográficos
Main Authors: Eastburn, Dennis J., Zegers, Mirjam M., Mostov, Keith E.
Formato: Artigo
Idioma:Inglês
Publicado: The Company of Biologists 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482320/
https://ncbi.nlm.nih.gov/pubmed/22623728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.108670
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