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Perspectives on translational and therapeutic aspects of SIRT1 in inflammaging and senescence

SIRT1, a type III protein deacetylase, is considered as a novel anti-aging protein involved in regulation of cellular senescence/aging and inflammation. SIRT1 level and activity are decreased during lung inflammaging caused by oxidative stress. The mechanism of SIRT1-mediated protection against infl...

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Detalhes bibliográficos
Main Authors: Yao, Hongwei, Rahman, Irfan
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482299/
https://ncbi.nlm.nih.gov/pubmed/22796566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2012.06.031
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