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SIRT1 as a therapeutic target in inflammaging of the pulmonary disease
OBJECTIVE: Chronic inflammation and cellular senescence are intertwined in the pathogenesis of premature aging, which is considered as an important contributing factor in driving chronic obstructive pulmonary disease (COPD). SIRT1, a NAD(+)-dependent protein/histone deacetylase, regulates inflammati...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3311735/ https://ncbi.nlm.nih.gov/pubmed/22178470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ypmed.2011.11.014 |
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