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SIRT1 as a therapeutic target in inflammaging of the pulmonary disease

OBJECTIVE: Chronic inflammation and cellular senescence are intertwined in the pathogenesis of premature aging, which is considered as an important contributing factor in driving chronic obstructive pulmonary disease (COPD). SIRT1, a NAD(+)-dependent protein/histone deacetylase, regulates inflammati...

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Main Authors: Rahman, Irfan, Kinnula, Vuokko L., Gorbunova, Vera, Yao, Hongwei
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311735/
https://ncbi.nlm.nih.gov/pubmed/22178470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ypmed.2011.11.014
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