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SIRT1 as a therapeutic target in inflammaging of the pulmonary disease
OBJECTIVE: Chronic inflammation and cellular senescence are intertwined in the pathogenesis of premature aging, which is considered as an important contributing factor in driving chronic obstructive pulmonary disease (COPD). SIRT1, a NAD(+)-dependent protein/histone deacetylase, regulates inflammati...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3311735/ https://ncbi.nlm.nih.gov/pubmed/22178470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ypmed.2011.11.014 |
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