Endogenous Angiogenesis Inhibitors Prevent Adaptive Capillary Growth in Left Ventricular Pressure Overload Hypertrophy

BACKGROUND: In left ventricular (LV) pressure-overload hypertrophy, lack of adaptive capillary growth contributes to progression to failure. Remodeling of the hypertrophied myocardium requires proteolysis of the extracellular matrix (ECM) carried out by matrix metalloproteinases (MMPs). MMPs, specif...

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Main Authors: Nikolova, Andriana, Ablasser, Klemens, Wyler von Ballmoos, Moritz C., Poutias, Dimitrios, Kaza, Elisabeth, McGowan, Francis X., Moses, Marsha A., del Nido, Pedro J., Friehs, Ingeborg
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482283/
https://ncbi.nlm.nih.gov/pubmed/22795062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.athoracsur.2012.05.052
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