Vascular endothelial growth factor delays onset of failure in pressure-overload hypertrophy through matrix metalloproteinase activation and angiogenesis

OBJECTIVE: Pressure-overload hypertrophy is associated with decreased capillary density in myocardium resulting in impaired substrate delivery. Treatment of hypertrophied hearts with vascular endothelial growth factor (VEGF) induces angiogenesis. Since angiogenesis is associated with extracellular m...

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Main Authors: Friehs, Ingeborg, Margossian, Renee E., Moran, Adrian M., Cao-Danh, Hung, Moses, Marsha A., del Nido, Pedro J.
Formato: Artigo
Idioma:Inglês
Publicado: 2005
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444246/
https://ncbi.nlm.nih.gov/pubmed/16369727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-005-0581-0
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