Vascular endothelial growth factor delays onset of failure in pressure-overload hypertrophy through matrix metalloproteinase activation and angiogenesis

OBJECTIVE: Pressure-overload hypertrophy is associated with decreased capillary density in myocardium resulting in impaired substrate delivery. Treatment of hypertrophied hearts with vascular endothelial growth factor (VEGF) induces angiogenesis. Since angiogenesis is associated with extracellular m...

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Bibliografiske detaljer
Main Authors: Friehs, Ingeborg, Margossian, Renee E., Moran, Adrian M., Cao-Danh, Hung, Moses, Marsha A., del Nido, Pedro J.
Format: Artigo
Sprog:Inglês
Udgivet: 2005
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444246/
https://ncbi.nlm.nih.gov/pubmed/16369727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-005-0581-0
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