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Impaired insulin-signaling in hypertrophied hearts contributes to ischemic injury

Despite increased glucose utilization by hypertrophied myocardium, these hearts exhibit a slower rate of glucose uptake (GU). We hypothesized that, in hypertrophied myocardium, a defect of the insulin-responsive glucose transporter is responsible for impaired GU and metabolism during ischemia, contr...

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Detalhes bibliográficos
Main Authors: Friehs, Ingeborg, Cao-Danh, Hung, Nathan, Meena, McGowan, Francis X., del Nido, Pedro J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444251/
https://ncbi.nlm.nih.gov/pubmed/15845351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2005.03.120
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